The global market for obesity medications is set for massive growth, with projections estimating it will reach $173.5 billion by 2031. This surge is being driven by rising obesity rates, increased awareness of health risks linked to excess weight, and the development of highly effective weight-loss drugs.
Rapid market expansion
According to a recent report, the obesity drug market is expected to grow at a compound annual growth rate (CAGR) of 24.7% from 2023 to 2031.
In the seven major markets (France, Germany, Italy, Japan, Spain, the UK, and the US), the growth rate is even higher, at 32.3%.
This rapid expansion is fueled by pharmaceutical advancements, improved access to healthcare, and shifting medical perspectives that recognize obesity as a chronic disease requiring long-term treatment.
Leading companies and breakthrough medications
Pharmaceutical giants Novo Nordisk and Eli Lilly currently dominate the market with their blockbuster weight-loss drugs.
Novo Nordisk’s Wegovy (semaglutide) and Eli Lilly’s Zepbound (tirzepatide) have demonstrated remarkable weight-loss benefits, making them highly sought after.
Analysts predict that these drugs will continue to drive revenue, while emerging biotech firms and pharmaceutical companies compete to introduce the next generation of obesity treatments.
Expanding treatment options
Currently, only a few medications are approved for obesity treatment, including:
- Combination therapies (bupropion-naltrexone, phentermine-topiramate)
- Lipase inhibitors (orlistat)
- Anorectics
- GLP-1 receptor agonists (Saxenda, Wegovy)
- Dual GLP-1/GIP receptor agonists (Mounjaro/Zepbound)
Among these, GLP-1 receptor agonists are revolutionizing obesity treatment, with some medications leading to up to 25% body weight loss.
The obesity drug pipeline is also expanding, with 141 products currently in clinical development, including incretin analogues and drugs with new mechanisms of action.
Market challenges and opportunities
Despite its promising outlook, the obesity drug market faces several challenges. High drug costs, supply chain issues, and long-term safety concerns could slow widespread adoption.
Additionally, regulatory agencies such as the FDA and EMA are working to streamline approval processes, ensuring new therapies reach patients more quickly.
On the other hand, the market presents significant growth opportunities. Insurers and healthcare providers are increasingly covering obesity treatments, improving patient access.
Newer drugs, such as Eli Lilly’s bimagrumab (BYM338) and Amgen’s MariTide, promise longer-lasting effects and improved patient compliance.
Additionally, innovative oral obesity medications like Novo Nordisk’s oral semaglutide (NN-9932) and Eli Lilly’s orforglipron are expected to widen treatment options.
The future of obesity treatment
With more than 200 million people in major global markets living with obesity, and this number expected to rise, the demand for effective treatments is set to increase.
As obesity is now widely recognized as a chronic disease, both doctors and patients are becoming more aware of available treatment options, leading to more diagnoses and higher demand for medications.
The market is currently dominated by Novo Nordisk and Eli Lilly, but with increasing investment and innovation, new players have an opportunity to enter this high-growth sector.
Given the strong connection between obesity and conditions such as diabetes and heart disease, the expansion of this market is expected to impact the entire cardiometabolic disease space.